SUDAFED PE ® Pressure + Pain + Cough Liquid provides temporary relief of sinus congestion and pressure, sore throat, coughing, and minor aches and pains. Each 15-milliliter dose contains 325 milligrams of acetaminophen for pain relief, fever reduction, and sinus headache relief; 5 milligrams of phenylephrine HCl for congestion relief; and 10 milligrams of dextromethorphan HBr to help suppress cough. It also helps promote nasal and sinus drainage. Formulated for daytime use, the non-drowsy sinus and cold medicine for adults features a fresh orange flavor.